Skip to content


137 reviews |
Original price $41.95 - Original price $41.95
Original price
$41.95 - $41.95
Current price $41.95
  • All-natural progesterone body creme derived from wild yam
  • Contains lavender essential oil

Note: Prescription required for shipment to Canada. 

Buy 3 or more to save 10%

Get ProgestaKey for $37.76 each when buying 3 or more!

Balance Your Hormones Naturally*

ProgestaKey is an all-natural Progesterone Crème sourced from wild yam for menopausal and peri-menopausal support.* Each pump of this topical creme conveniently delivers the recommended dosage of 20 mg of USP progesterone per pump and is scented with lavender essential oil.

Progesterone, not estrogen, is often the first hormone to decline during the peri-menopausal years. According to Harvard research, it's estimated that by age 35, the typical woman is already deficient in progesterone.

Progesterone has benefits far beyond its role in menstrual cycles and pregnancy, and lack of this essential hormone can affect many of the body's systems.

Signs of progesterone deficiency:

  • Frequent hot flashes and night sweats*
  • Emotional Swings*
  • Weight gain, especially around the tummy*
  • Lack or decrease in sex drive*
  • Exhaustion/low energy*

Benefits of proper progesterone levels:

  • Reduction of menopausal symptoms
  • Improved hormone balance
  • Stimulation of bone formation and prevention of osteoporosis
  • Stabilization of zinc-copper balance
  • Enhanced sex drive
  • Metabolism of fat
  • Promotion of a sense of well-being

If you're unsure if you're in need of Progesterone, consider an at-home Salivary Hormone Test to evaluate your hormone levels.

ProgestaKey Ingredients:

Purified water, aloe vera gel, caprylic/capric triglycerides, natural progesterone USP, evening primrose oil, vitamin E acetate, MSM (methyl sulfonylmethane), isostearic acid, yarrow extract, cranberry extract, glyceryl stearate, shea butter, lecithin, glycerine USP, lavender essential oil, vanilla extract, allantoin, sorbic acid, and grapeseed extract.

IMPORTANT for Canadian Customers:  Due to Health Canada restrictions, Natural Progesterone Crème requires a prescription for shipment to Canada. In order for your order to be processed, send us a copy of a current prescription from a licensed physician in Canada. 


Q: Can I use this with other HRT?
A: Yes, though it may be a good idea to evaluate your hormone levels with a Salivary Hormone Test. Also, if using hormonal contraceptives, please use back up method of birth control.

Q: Do I have to use this forever?
A: Progesterone is important for many aspects of health in women of all ages- from balanced monthly cycles and mood swings to relieving hot flashes and night sweats and supporting healthy bones.* You may use ProgestaKey long term, or just as long as you want to help manage symptoms.

Q: Do I need to rotate the site of application?
A: Yes, we recommend rotating the site of application every week to prevent saturating the progesterone receptors in your skin. For instance, week one apply to chest and neck, week two to abdomen, week three to inner arms and inner thighs.

Q: My cycle is irregular. How do I decide when to start and stop ProgestaKey?
A: It's common for a woman's cycle to be as short as 20 days and as long as 40. Day 1 of your cycle is considered the first day of menstruation. The basic instructions for menstruating women advise using the creme from day 12 to 26. If your menses begins before day 26, simply stop using the creme when it begins, and resume again on day 12. If your menses is still happening by day 12, still begin using the creme as scheduled. If you experience spotting, stick to the regular schedule. If the spotting is so prevalent that you can't discern your true menses, simply use the creme for two weeks each month and keep consistent to that schedule.

Q: I've had a hysterectomy. How should I use ProgestaKey?
A: Please follow the directions for menopausal women, applying the creme for 25 consecutive days and then taking a 5 day break.

Q: I want to do the salivary hormone test. Can I still use ProgestaKey?
A: To achieve an accurate reading, we recommend abstaining from the creme for at least 3-5 days prior to collecting your saliva sample. Menstruating women should collect their saliva on days 19, 20, or 21 of their cycle, so consider skipping ProgestaKey all together that cycle. Menopausal women can collect their saliva any day of the month, so aim to do so on the final day of the 5 day break from ProgestaKey.



For optimum absorption, apply ProgestaKey to the neck area. Refer to the 'Suggested Use' section on the label for more complete directions regarding specific frequency and dosage according to your age and stage of life. Wash hands after applying.


Purified water, aloe vera gel, caprylic/capric triglycerides, natural progesterone USP, evening primrose oil, vitamin E acetate, MSM (methyl sulfonylmethane), isostearic acid, yarrow extract, cranberry extract, glyceryl stearate, shea butter, lecithin, glycerine USP, lavender essential oil, vanilla extract, allantoin, sorbic acid, and grapeseed extract.



May not be appropriate for pregnant and/or nursing women. If using ProgestaKey with birth control, it is recommended for use only once every 3 days during the last 2 weeks of your cycle. Consult your health care practitioner for specific instructions.

Why Buy From Us?

ProgestaKey is manufactured in the USA at a Good Manufacturing Practices (GMP) and FDA registered facility. Each finished product must meet stringent quality standards.

Every batch of ProgestaKey is then third-party tested to confirm it meets the highest standards for purity, and every third batch is third-party tested for heavy metals.

100% Satisfaction Guarantee

We believe you’ll love the benefits of ProgestaKey. Try ProgestaKey today with complete confidence thanks to our 100% Satisfaction 90-Day Money-Back Guarantee.

If you’re dissatisfied with ProgestaKey for any reason please give us a call at 800-888-4353 or email and we’ll make it right.

Customer Reviews
4.7 Based on 137 Reviews
5 ★
4 ★
3 ★
2 ★
1 ★
Customer Photos
Write a Review Ask a Question

Thank you for submitting a review!

Your input is very much appreciated. Share it with your friends so they can enjoy it too!

Filter Reviews:
Gina R.
United States United States

ProgestaKey is Awesome!

ProgestaKey is awesome! I've been using this product for years, now that I am full on menopause it has helped me with many symptoms!


UNI KEY Health

Thanks for your great review Gina! We're so happy to hear that Progesta-Key is helping with your menopause symptoms. Thanks again! In good health, UNI KEY Staff

Kathleen M.
United States United States

Helps with self esteem!

I have been using this product since I was 40 and I am now 66. It truly helps with hot flashes, mood swings and weight gain. I feel more energetic because I do not have the crazy hot flashes, etc. I go to the gym and workout 3-4 days a week plus walk 3 miles 5 days a week. I do yoga in the mornings on 5 days and it does not matter which days just so I do it 5 times in a week.

Erica C.
United States United States

It works but it's very thick and sticky

I have used this item for years. It works or I wouldn't keep buying it, but it is very thick and sticky. I wish there was a lighter weight version that maybe even used less product, as it's a challenge to decide where on my body I want the sticky cream (especially in the summer or when wearing nice clothes). My husband does not like me having the sticky feeling either, it but until I can find a better alternative I'll be using it.

Elise P.
United States United States

ProgestaKey Cream

Impossible to get product after pumping several hundred pumps.


UNI KEY Health

Hi Elise, Thank you for your review. We're so sorry, it sounds like you received a faulty pump. Please call customer service so that we can make this right for you. 800-888-4353. In good health, UNI KEY Staff

Nadyaris V.
United States United States

Feeling Fantastic

Thanks so much for designing this product. The natural ingredients, the amount and directions set me up for success.


UNI KEY Health

Thanks for your great review, Nadyaris! We're pleased to hear that you're having great success with Progesta-Key and feeling fantastic! Keep us updated. In good health, UNI KEY Staff

Phyllis P.
United States United States


Very Good! Quit asking so many questions