3 Ounce Bottle (60-Day Supply)
  • Availability: In Stock

Topical use of this creme may help retain and/or regain hormonal balance.*

  • All-natural progesterone creme derived from wild yam
  • Petrochemical-free
  • Contains lavender essential oil

Note: Prescription required for shipment to Canada. 

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Balance Your Hormones Naturally*

ProgestaKey is an all-natural progesterone creme sourced from wild yam for menopausal and peri-menopausal support.*

Progesterone, not estrogen, is often the first hormone to decline during the peri-menopausal years. According to Harvard research, it's estimated that by age 35, the typical woman is already deficient in progesterone.

Progesterone has benefits far beyond its role in menstrual cycles and pregnancy, and lack of this essential hormone can affect many of the body's systems.

Signs of progesterone deficiency:

  • Frequent hot flashes and night sweats*
  • Emotional Swings*
  • Weight gain, especially around the tummy*
  • Lack or decrease in sex drive*
  • Exhaustion/low energy*

Benefits of proper progesterone levels:

  • Reduction of menopausal symptoms
  • Improved hormone balance
  • Stimulation of bone formation and prevention of osteoporosis
  • Stabilization of zinc-copper balance
  • Enhanced sex drive
  • Metabolism of fat
  • Promotion of a sense of well-being

ProgestaKey is dispensed in a pump-style container that conveniently delivers the recommended dosage of 20 mg per pump and also contains lavender essential oil.

Ingredients: Purified water, aloe vera gel, caprylic/capric triglycerides, natural progesterone USP, evening primrose oil, vitamin E acetate, MSM (methyl sulfonylmethane), isostearic acid, yarrow extract, cranberry extract, glyceryl stearate, shea butter, lecithin, glycerine USP, lavender essential oil, vanilla extract, allantoin, sorbic acid, and grapeseed extract.

IMPORTANT for Canadian Customers:  Due to Health Canada restrictions, Natural Progesterone Creme requires a prescription for shipment to Canada. In order for your order to Canada to be processed, you will need to send us a copy of a current prescription from a licensed physician in Canada. 

ProgestaKey Product Information Sheet


Q: How do I know if I need ProgestaKey?
A: In many women, progesterone deficiency can manifest as PMS and difficult menses, mood swings and depression, low fertility, forgetfulness, hot flashes, night sweats, weak and brittle bones. If you relate to any of those symptoms, you may benefit from using ProgestaKey.

Q: Can I use this with other HRT?
A: Yes, though it may be a good idea evaluate your hormone levels with a Salivary Hormone Test. Also, if using hormonal contraceptives, please use back up method of birth control.

Q: My doctor put me on estrogen HRT. Should I stop that when I start ProgestaKey?
A: Please do not discontinue any prescriptions without first discussing with your doctor. Many women experience relief from most of the negative hormonal symptoms simply by adding progesterone, so ProgestaKey may be all you need to alleviate your symptoms. Best to discuss with your doctor.

Q: Do I have to use this forever?
A: Progesterone is important for many aspects of health in women of all ages- managing PMS and heavy cycles, mood swings, optimizing fertility, reducing hot flashes and night sweats, supporting bone health. You may use ProgestaKey long term, or just as long as you want to help manage symptoms.

Q: Do I need to rotate the sight of application?
A: Yes, we recommend rotating the site of application every week to prevent saturating the progesterone receptors in your skin. For instance, week one apply to chest and neck, week two to abdomen, week three to inner arms and inner thighs.

Q: My cycle is irregular. How do I decide when to start and stop ProgestaKey?
A: It's common for a woman's cycle to be as short as 20 days and as long as 40. Day 1 of your cycle is considered the first day of menstruation. The basic instructions for menstruating women advise using the creme from day 12 to 26. If your menses begins before day 26, simply stop using the creme when it begins, and resume again on day 12. If your menses is still happening by day 12, still begin using the creme as scheduled. If you experience spotting, stick to the regular schedule. If the spotting is so prevalent that you can't discern your true menses, simply use the creme for two weeks each month and keep consistent to that schedule.

Q: I've had a hysterectomy. How should I use ProgestaKey?
A: Please follow the directions for menopausal women, applying the creme for 25 consecutive days and then taking a 5 day break.

Q: I want to do the salivary hormone test. Can I still use ProgestaKey?
A: To achieve an accurate reading, we recommend abstaining from the creme for at least 3-5 days prior to collecting your saliva sample. Menstruating women should collect their saliva on days 19, 20, or 21 of their cycle, so consider skipping ProgestaKey all together that cycle. Menopausal women can collect their saliva any day of the month, so aim to do so on the final day of the 5 day break from ProgestaKey.

Q: Should I wash my hands after applying ProgestaKey?
A: Yes, especially if you have contact with children, pets, or loved ones.

Q: I've had cancer. Can I still use ProgestaKey?
A: It is impossible for us to know, so we encourage you to speak to your health care provider about the potential benefits of naturally derived progesterone.

For optimum absorption, apply ProgestaKey to the neck area. Refer to the 'Suggested Use' section on the label for more complete directions regarding specific frequency and dosage according to your age and stage of life.

Ingredients: Purified water, aloe vera gel, caprylic/capric triglycerides, natural progesterone USP, evening primrose oil, vitamin E acetate, MSM (methyl sulfonylmethane), isostearic acid, yarrow extract, cranberry extract, glyceryl stearate, shea butter, lecithin, glycerine USP, lavender essential oil, vanilla extract, allantoin, sorbic acid, and grapeseed extract.


May not be appropriate for pregnant and/or nursing women. If using ProgestaKey with birth control, it is recommended for use only once every 3 days during the last 2 weeks of your cycle. Consult your health care practitioner for specific instructions.

Please Note: Due to Canadian FDA regulations, UNI KEY is unable to ship this product to Canada without a prescription.

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