ReelUp tracking pixel Read the Privacy Policy
Skip to content

"This product really makes a difference for my digestion. I experience much less bloating and feel good after meals when I take Digesta-Key. Definitely a game changer 😀"
– Nolana M.

 Verified buyer

Digesta-Key

pancreatic enzyme support for complete digestion

Powerful, all-natural digestive enzyme formula to help your body break down and absorb nutrients more efficiently!

• MULTI-ENZYME FORMULA – Includes a complete range of enzymes to support digestion of proteins, fats, starches, and more.

• HELPS REDUCE BLOATING & GAS – Aids the breakdown of hard-to-digest foods to ease digestive discomfort, maintain intestinal health and minimize food intolerances.

• IMPROVES NUTRIENT ABSORPTION – Ensures your body can effectively absorb vitamins and minerals for optimal health, boosting immunity, and supporting joint health and mobility.

Quantity

Highlights

Digestive enzymes are essential for breaking down food—but many people don’t produce enough, especially with age, stress, or processed diets. Digesta-Key fills this gap with a powerful blend of pancreatic enzymes and plant-based enzymes like bromelain, papain, and serrapeptase.


The acid-resistant capsules are designed to withstand stomach acid and deliver enzymes directly to the small intestine for maximum absorption and effectiveness. If you’re experiencing gas, bloating, indigestion, or nutrient malabsorption, Digesta-Key helps restore digestive power and comfort with every meal!

How to Use

Take three to five (3 - 5) capsules daily on an empty stomach, or as directed by your healthcare practitioner.


Note: Individuals taking blood thinners or other medication as well as those with bleeding disorders or liver damage should discuss potential interactions and contraindications with their healthcare practitioner.

Product Facts

Form: Capsule

Serving Size: 5 capsules

Number of Servings: 20

Contains No: gluten, soy, dairy, fish, shellfish, peanuts, tree nuts, egg, GMOs, artificial colors, artificial sweeteners, or artificial preservatives.

Free Shipping Over $99

90 Day Returns

Secure Online Payment

Product Image

Unlock the Power of Complete Digestion

Advanced Enzyme Support
Digesta-Key’s comprehensive blend of enzymes helps break down all types of foods—proteins, carbs, fats, and fibers—ensuring better digestion and nutrient absorption.

Relieves Digestive Discomfort
If you struggle with bloating, gas, or indigestion, Digesta-Key can help alleviate these symptoms by supporting smoother digestion and gut function.

Boosts Nutrient Absorption
By improving the breakdown of food, Digesta-Key ensures your body absorbs vitamins, minerals, and nutrients more efficiently, so you feel more nourished and energized.

Ideal for Sensitive Stomachs
With enzymes that target even the most fibrous foods, Digesta-Key is gentle enough for those with sensitive digestive systems while still being effective in promoting overall gut health.

Superior Ingredients For Results You Can Feel

As we age, our bodies produce fewer digestive enzymes—making it harder to break down food, absorb nutrients, and avoid post-meal discomfort. Digesta-Key is a uniquely balanced blend of powerful porcine-derived and plant-based enzymes that support complete digestion, from start to finish.

Unlike many digestive aids that focus on just one food group, Digesta-Key helps break down protein, fat, starch, and fiber. Whether you're eating a high-protein diet, recovering from digestive issues, or just want smoother digestion after meals, Digesta-Key is your go-to daily enzyme support.

  • Key Ingredients

  • Full List of Ingredients

  • Supplement Facts

Pancreatic Protease, Amylase & Lipase (porcine)

These foundational enzymes help break down proteins, carbohydrates, and fats to optimize digestion and nutrient absorption.


Rutin

A natural antioxidant that supports vascular health and enhances the activity of systemic enzymes.


Bromelain

A pineapple-derived enzyme that helps digest protein and supports a healthy inflammation response.


Trypsin & Chymotrypsin (porcine)

Two powerful pancreatic enzymes that aid in protein digestion and support post-workout recovery and tissue repair.


Papain

Derived from papaya, this enzyme promotes protein digestion and eases occasional digestive discomfort.


Serrapeptase

A unique enzyme known for its systemic benefits, supporting joint, sinus, and tissue health throughout the body.

Pancreatic Protease (porcine), Pancreatic Amylase (porcine), Pancreatic Lipase (porcine), Rutin, Bromelain, Trypsin (porcine), Chymotrupsin (porcine), Papain, Serrapeptase. Other Ingredients: Hypromellose, Gellan Gum, Inulin, Stearic Acid, Magnesium Stearate, Silica.

Product Image

Questions? We've Got Answers!

How should I take Digesta-Key for the best results?

For optimal absorption, take Digesta-Key on an empty stomach, preferably 15-30 minutes before meals. This ensures the enzymes are absorbed directly into your bloodstream and can support digestion effectively.

Can Digesta-Key help with joint health?

Yes! The enzymes in Digesta-Key help maintain tissue integrity and support the body's natural ability to heal, promoting joint health, flexibility, and mobility, especially after injury or stress. A randomized double-blind controlled study using systemic enzyme therapy (a combination of bromelain, trypsin, and rutin) reported “remarkable differences” in tissue comfort and integrity in subjects who received the enzyme therapy.*

How does Digesta-Key support immune system balance?

The enzymes in Digesta-Key, such as bromelain and serrapeptase, help promote a balanced immune system by supporting immune function and regulating cytokine production, leading to improved overall immune health.

Can Digesta-Key help with inflammation?

Yes, Digesta-Key helps regulate eicosanoid production and cytokine balance, which plays a key role in maintaining a healthy inflammatory response and supporting tissue recovery.

What's the difference between Digesta-Key, HCL+2, and Bile Builder?

Great question! These digestive supplements each support different parts of digestion. Digesta-Key helps break down food with a full spectrum of enzymes, HCL+2 supports healthy stomach acid for protein and fat digestion, and Bile Builder promotes bile flow for optimal fat and nutrient absorption.

Read more about the differences and which one will work best for you here.

Our Customers Say It Best

"I have been taking Digesta-Key for close to a year. I have arthritis and I do not have a gallbladder so my fat digestion is compromised. These supplements have been very helpful for digestion, as well as joint comfort. I highly recommend it!"
– Mimi

"I love these digestive enzymes, used along with Uni Key's probiotic powder, Flora-Key, I feel like it helps my gut health greatly. I make sure I never miss a day taking them!"
– Laurie A.

"Taking two Digesta-Key first thing in the morning with a full glass of water has helped my digestive problems. I would have horrible lower tract issues every day and now that I take Digesta-Key I haven't had any issues with my gut!"
– Elaine R.

Recommended by Ann Louise Gittleman, PhD, CNS

Top Nutritionist & New York Times Bestselling Author

"So many of the digestive issues I see—from bloating and gas to food sensitivities and poor nutrient absorption—can be traced back to one thing: enzyme deficiency. That's why I recommend Digesta-Key to almost everyone. It's one of the most comprehensive enzyme formulas available and works on all three macronutrients: protein, carbs, and fats.

What makes Digesta-Key unique is its powerful combination of porcine pancreatic enzymes and plant-based enzymes like bromelain and papain. This synergistic formula helps digest even the heaviest meals and supports your body’s ability to absorb and use the nutrients from your food.

Whether you're dealing with occasional discomfort or long-standing digestive concerns, Digesta-Key gives your body the missing tools it needs for smoother digestion and better overall vitality."

Why Buy from UNI KEY?

Our Quality Promise

At UNI KEY Health, we are committed to providing the highest quality supplements. Our products are manufactured in the USA at a Good Manufacturing Practices (GMP) and FDA-registered facility. Each batch undergoes rigorous testing for purity, potency, and heavy metals to ensure you receive only the best.

100% Satisfaction Guarantee

We stand behind every product we offer with our 90-Day Money-Back Guarantee. If you're not completely satisfied for any reason, simply call us at 1-800-888-4353 or email info@unikeyhealth.com, and we’ll make it right. 

We invite you to try UNI KEY Health products today—RISK FREE! 

You May Also Like...

Verified Customer Reviews

Customer Reviews

Based on 33 reviews
79%
(26)
0%
(0)
6%
(2)
3%
(1)
12%
(4)
M
Maria

Very satisfied with this purchase; great supplement!!

Thanks so much for your great review Maria! We're so glad to hear Digesta-Key is working for you. Thank you for choosing UNI KEY :)

E
Elaine R.

In the past I had digestion issues especially after breakfast, however, after taking two of these capsules every morning with an 8oz glass of water my digestive issues are gone. I have been using Digesta-key for over 10 years. I am a petite person so only take two, but you can take more if your body type is different.

Hi Elaine, thank you for sharing your experience with Digesta-Key. We are thrilled to hear that it has helped with your digestion issues for over 10 years! Thank you for your support and for making us a part of your health journey :)

K
Kelly L.

Best products I’ve ever used. They have been most helpful.

Thank you so much for your kind words, Kelly! We’re thrilled to hear that our products have been so helpful for you. Your support means a lot to us!

C
Claire M.

Thank you Unikey, such a good product!

K
Kathleen P.
Works well

I started using this a month or so ago. My digestion does seem to be more effective. Will keep using it.

{"id":4353697120290,"title":"Digesta-Key","handle":"digesta-key","description":"\u003ch2\u003eOptimize digestion with pancreatic enzyme supplements\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDigesta-Key\u003c\/strong\u003e provides a diverse combination of pancreatic enzymes and anti-inflammatory enzymes with antioxidants and metabolic cofactors including \u003cspan\u003epancreatin, papain, rutin, bromelain, trypsin, chymotrypsin, and serrapeptase\u003c\/span\u003e.\u003c\/p\u003e\n\u003cp\u003eThese digestive enzyme capsules reportedly aid the small intestine's role in digesting proteins, fats and carbohydrates. Their actions are thought to help maintain intestinal health and minimize food intolerances. \u003c\/p\u003e\n\u003cp\u003eThis pancreatic enzyme supplement is specially coated to resist stomach acid. The coating is pH factored to release in the upper part of the small intestine where food synthesis occurs. \u003c\/p\u003e\n\u003ch3\u003eHow Pancreatic Enzymes Work\u003c\/h3\u003e\n\u003cp\u003eEnzymes are complex proteins that catalyze metabolic reactions throughout the body, and sufficient levels are necessary for optimizing many bodily functions. Though the body naturally produces its own supply of enzymes, production can vary with age and biochemical individuality.*[1]\u003c\/p\u003e\n\u003cp\u003eProteolytic enzymes, also known as proteases, specifically break down proteins into peptides and amino acids through the process of “proteolysis.” For example, proteases produced by the pancreas assist in the digestion of dietary protein. Some proteases, such as trypsin, are then reabsorbed, transported in the bloodstream, and resecreted by the pancreas. Enzymes in circulation are bound to antiprotease alpha-2-macroglobulin to protect them from being degraded by other serum proteases and to retain their enzymatic activity.*\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDigesta-Key\u003c\/strong\u003e is a proteolytic enzyme formula designed to be absorbed across the gastrointestinal mucosa and into circulation.[2] When distributed systemically, proteolytic enzymes can break down proteins and complexes generated during injury and tissue damage. This action supports the body’s normal recovery process.* In vivo studies suggest that trypsin and other proteases, though normally confined to the bloodstream, are able to enter the site of injury.[3] At this site, they are able to support immune function and affect cytokine production. Research suggests that orally administered proteolytic enzymes may exert this beneficial effect as well.[3,4] It is thought that they function as proteinase-activated receptor (PAR) modulators, a feature which allows them to contribute to immune and cytokine balance.[5] Proteolysis of intestinal microorganisms may contribute to the immunostimulatory effects of oral proteolytic enzymes as well.*[6] Proteolytic enzymes have been used worldwide for decades to support health and healing. For example, research on bromelain (an enzyme obtained from pineapple) suggests that it positively affects eicosanoid production and balance.[7-9] Furthermore, it is suggested that bromelain supports the body’s innate and adaptive immune function,[10,11] signifying an effect beyond that of proteolysis in some cases.* Serrapeptase (also known as serratiopeptidase) is an enzyme produced by microorganisms in the gastrointestinal tract of silkworms. Silkworms use it to digest their cocoons. Multicenter, double-blind studies suggest that serrapeptase significantly supports tissue integrity and comfort and is well-tolerated.[12,13]\u003c\/p\u003e\n\u003cp\u003ePancreatin in this pancreatic enzyme supplement is a mixture of pancreactic enzymes containing chymotrypsin, trypsin, amylase, and lipase. The papain present is a proteolytic enzyme derived from papaya fruit.* The effect of combining various proteolytic enzymes has been studied closely for decades. For example, the combination of trypsin and chymotrypsin has a history of use in the support of tissue integrity and healing, with positive results in early double-blind trials.[14-16]\u003c\/p\u003e\n\u003cp\u003eThe combination of bromelain, trypsin, and rutin has been researched and found to produce positive results as well.[17] For example, in a six-week, randomized, double-blind, parallel group trial (n=90), oral proteolytic enzymes were well-tolerated and positively affected clinical outcomes, including Western Ontario and McMaster Universities osteoarthritis index (WOMAC) and Lequesne’s index scores, as efficiently as other compounds studied.[18]\u003c\/p\u003e\n\u003cp\u003eAnother randomized double-blind controlled study using systemic enzyme therapy (a combination of bromelain, trypsin, and rutin) reported “remarkable differences” in tissue comfort and integrity in subjects who received the enzyme therapy.*[19]\u003c\/p\u003e\n\u003cp\u003eDigesta-Key contains a combination of pancreatin, papain, rutin, bromelain, trypsin, chymotrypsin, and serrapeptase in acid-resistant capsules that are designed to withstand gastric juices, ultimately allowing direct absorption into the bloodstream. For best results, the formula should be consumed on an empty stomach.*\u003c\/p\u003e","published_at":"2020-01-03T13:04:10-08:00","created_at":"2019-11-25T12:48:20-08:00","vendor":"Uni Key Health Systems, Inc","type":"Supplements","tags":["All Products","bromelain","bundle-available","chymotrypsin","Digestive Health","Essential Nutrition","Health Concern_Digestive Health","Health Concern_Immune Support","Health Concern_Joint Support","Immune Support","Joint Support","pancreatin 10x","papain","Product Type_All Products","Product Type_Supplements","rutin","serrapeptase","trypsin","Wellness"],"price":5578,"price_min":5578,"price_max":5578,"available":true,"price_varies":false,"compare_at_price":null,"compare_at_price_min":0,"compare_at_price_max":0,"compare_at_price_varies":false,"variants":[{"id":31224320458786,"title":"Default Title","option1":"Default Title","option2":null,"option3":null,"sku":"7070","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Digesta-Key","public_title":null,"options":["Default Title"],"price":5578,"weight":91,"compare_at_price":null,"inventory_quantity":30,"inventory_management":"shopify","inventory_policy":"deny","barcode":"","requires_selling_plan":false,"selling_plan_allocations":[{"price_adjustments":[{"position":1,"price":4741}],"price":4741,"compare_at_price":5578,"per_delivery_price":4741,"selling_plan_id":1737523234,"selling_plan_group_id":"971df5175e0e859afc41a07632246ddbfbe19959"},{"price_adjustments":[{"position":1,"price":4741}],"price":4741,"compare_at_price":5578,"per_delivery_price":4741,"selling_plan_id":1737588770,"selling_plan_group_id":"5e74003bb59382599f49b038fa63a17ffcf2c497"},{"price_adjustments":[{"position":1,"price":4741}],"price":4741,"compare_at_price":5578,"per_delivery_price":4741,"selling_plan_id":1737556002,"selling_plan_group_id":"eafa08c88ca5550e4a9cf9648104105929a1cf2b"}],"quantity_rule":{"min":1,"max":null,"increment":1}}],"images":["\/\/unikeyhealth.com\/cdn\/shop\/products\/Digesta-Key-square.png?v=1615234738","\/\/unikeyhealth.com\/cdn\/shop\/files\/Digesta-Key_label_updated.jpg?v=1741983182"],"featured_image":"\/\/unikeyhealth.com\/cdn\/shop\/products\/Digesta-Key-square.png?v=1615234738","options":["Title"],"media":[{"alt":"The front of a bottle of Digesta-Key, a pancreatic enzyme formula supplement with 100 acid-resistant vegetarian capsules.","id":20276768178210,"position":1,"preview_image":{"aspect_ratio":1.0,"height":1200,"width":1200,"src":"\/\/unikeyhealth.com\/cdn\/shop\/products\/Digesta-Key-square.png?v=1615234738"},"aspect_ratio":1.0,"height":1200,"media_type":"image","src":"\/\/unikeyhealth.com\/cdn\/shop\/products\/Digesta-Key-square.png?v=1615234738","width":1200},{"alt":null,"id":27039451676706,"position":2,"preview_image":{"aspect_ratio":1.0,"height":2000,"width":2000,"src":"\/\/unikeyhealth.com\/cdn\/shop\/files\/Digesta-Key_label_updated.jpg?v=1741983182"},"aspect_ratio":1.0,"height":2000,"media_type":"image","src":"\/\/unikeyhealth.com\/cdn\/shop\/files\/Digesta-Key_label_updated.jpg?v=1741983182","width":2000}],"requires_selling_plan":false,"selling_plan_groups":[{"id":"971df5175e0e859afc41a07632246ddbfbe19959","name":"Every 30 days","options":[{"name":"Recharge Plan ID","position":1,"values":["1413119"]},{"name":"Order Frequency and Unit","position":2,"values":["30-day"]},{"name":"Product Quantity","position":3,"values":["0"]}],"selling_plans":[{"id":1737523234,"name":"Every 30 days","description":null,"options":[{"name":"Recharge Plan ID","position":1,"value":"1413119"},{"name":"Order Frequency and Unit","position":2,"value":"30-day"},{"name":"Product Quantity","position":3,"value":"0"}],"recurring_deliveries":true,"price_adjustments":[{"order_count":null,"position":1,"value_type":"percentage","value":15}],"checkout_charge":{"value_type":"percentage","value":100}}],"app_id":"294517"},{"id":"5e74003bb59382599f49b038fa63a17ffcf2c497","name":"Every 60 days","options":[{"name":"Recharge Plan ID","position":1,"values":["1413121"]},{"name":"Order Frequency and Unit","position":2,"values":["60-day"]},{"name":"Product Quantity","position":3,"values":["0"]}],"selling_plans":[{"id":1737588770,"name":"Every 60 days","description":null,"options":[{"name":"Recharge Plan ID","position":1,"value":"1413121"},{"name":"Order Frequency and Unit","position":2,"value":"60-day"},{"name":"Product Quantity","position":3,"value":"0"}],"recurring_deliveries":true,"price_adjustments":[{"order_count":null,"position":1,"value_type":"percentage","value":15}],"checkout_charge":{"value_type":"percentage","value":100}}],"app_id":"294517"},{"id":"eafa08c88ca5550e4a9cf9648104105929a1cf2b","name":"Every 90 days","options":[{"name":"Recharge Plan ID","position":1,"values":["11150304"]},{"name":"Order Frequency and Unit","position":2,"values":["90-day"]},{"name":"Product Quantity","position":3,"values":["0"]}],"selling_plans":[{"id":1737556002,"name":"Every 90 days","description":null,"options":[{"name":"Recharge Plan ID","position":1,"value":"11150304"},{"name":"Order Frequency and Unit","position":2,"value":"90-day"},{"name":"Product Quantity","position":3,"value":"0"}],"recurring_deliveries":true,"price_adjustments":[{"order_count":null,"position":1,"value_type":"percentage","value":15}],"checkout_charge":{"value_type":"percentage","value":100}}],"app_id":"294517"}],"content":"\u003ch2\u003eOptimize digestion with pancreatic enzyme supplements\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDigesta-Key\u003c\/strong\u003e provides a diverse combination of pancreatic enzymes and anti-inflammatory enzymes with antioxidants and metabolic cofactors including \u003cspan\u003epancreatin, papain, rutin, bromelain, trypsin, chymotrypsin, and serrapeptase\u003c\/span\u003e.\u003c\/p\u003e\n\u003cp\u003eThese digestive enzyme capsules reportedly aid the small intestine's role in digesting proteins, fats and carbohydrates. Their actions are thought to help maintain intestinal health and minimize food intolerances. \u003c\/p\u003e\n\u003cp\u003eThis pancreatic enzyme supplement is specially coated to resist stomach acid. The coating is pH factored to release in the upper part of the small intestine where food synthesis occurs. \u003c\/p\u003e\n\u003ch3\u003eHow Pancreatic Enzymes Work\u003c\/h3\u003e\n\u003cp\u003eEnzymes are complex proteins that catalyze metabolic reactions throughout the body, and sufficient levels are necessary for optimizing many bodily functions. Though the body naturally produces its own supply of enzymes, production can vary with age and biochemical individuality.*[1]\u003c\/p\u003e\n\u003cp\u003eProteolytic enzymes, also known as proteases, specifically break down proteins into peptides and amino acids through the process of “proteolysis.” For example, proteases produced by the pancreas assist in the digestion of dietary protein. Some proteases, such as trypsin, are then reabsorbed, transported in the bloodstream, and resecreted by the pancreas. Enzymes in circulation are bound to antiprotease alpha-2-macroglobulin to protect them from being degraded by other serum proteases and to retain their enzymatic activity.*\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDigesta-Key\u003c\/strong\u003e is a proteolytic enzyme formula designed to be absorbed across the gastrointestinal mucosa and into circulation.[2] When distributed systemically, proteolytic enzymes can break down proteins and complexes generated during injury and tissue damage. This action supports the body’s normal recovery process.* In vivo studies suggest that trypsin and other proteases, though normally confined to the bloodstream, are able to enter the site of injury.[3] At this site, they are able to support immune function and affect cytokine production. Research suggests that orally administered proteolytic enzymes may exert this beneficial effect as well.[3,4] It is thought that they function as proteinase-activated receptor (PAR) modulators, a feature which allows them to contribute to immune and cytokine balance.[5] Proteolysis of intestinal microorganisms may contribute to the immunostimulatory effects of oral proteolytic enzymes as well.*[6] Proteolytic enzymes have been used worldwide for decades to support health and healing. For example, research on bromelain (an enzyme obtained from pineapple) suggests that it positively affects eicosanoid production and balance.[7-9] Furthermore, it is suggested that bromelain supports the body’s innate and adaptive immune function,[10,11] signifying an effect beyond that of proteolysis in some cases.* Serrapeptase (also known as serratiopeptidase) is an enzyme produced by microorganisms in the gastrointestinal tract of silkworms. Silkworms use it to digest their cocoons. Multicenter, double-blind studies suggest that serrapeptase significantly supports tissue integrity and comfort and is well-tolerated.[12,13]\u003c\/p\u003e\n\u003cp\u003ePancreatin in this pancreatic enzyme supplement is a mixture of pancreactic enzymes containing chymotrypsin, trypsin, amylase, and lipase. The papain present is a proteolytic enzyme derived from papaya fruit.* The effect of combining various proteolytic enzymes has been studied closely for decades. For example, the combination of trypsin and chymotrypsin has a history of use in the support of tissue integrity and healing, with positive results in early double-blind trials.[14-16]\u003c\/p\u003e\n\u003cp\u003eThe combination of bromelain, trypsin, and rutin has been researched and found to produce positive results as well.[17] For example, in a six-week, randomized, double-blind, parallel group trial (n=90), oral proteolytic enzymes were well-tolerated and positively affected clinical outcomes, including Western Ontario and McMaster Universities osteoarthritis index (WOMAC) and Lequesne’s index scores, as efficiently as other compounds studied.[18]\u003c\/p\u003e\n\u003cp\u003eAnother randomized double-blind controlled study using systemic enzyme therapy (a combination of bromelain, trypsin, and rutin) reported “remarkable differences” in tissue comfort and integrity in subjects who received the enzyme therapy.*[19]\u003c\/p\u003e\n\u003cp\u003eDigesta-Key contains a combination of pancreatin, papain, rutin, bromelain, trypsin, chymotrypsin, and serrapeptase in acid-resistant capsules that are designed to withstand gastric juices, ultimately allowing direct absorption into the bloodstream. For best results, the formula should be consumed on an empty stomach.*\u003c\/p\u003e"}