The Science Behind Radical Metabolizer: 5 Ingredients That Make a Difference

A root from the mint family got us thinking about what happens inside a fat cell. It’s called coleus root, and it contains forskolin, a compound researchers use to study how fat cells release the fat they’ve stored. That’s the first step your body takes when it draws on those reserves for fuel, and it’s why coleus root extract earned a place in Radical Metabolizer.

We had a different reason for choosing each of the other four ingredients. L-carnitine helps explain what happens after fat leaves storage. African mango seed extract caught our eye for another reason entirely. Researchers pulled out a tape measure as well as a scale.

WEIGHT MANAGEMENT SUPPORT

Radical Metabolizer

Five carefully selected ingredients to support your body's natural fat metabolism.

• ✓ Supports the body's natural fat metabolism
• ✓ Features forskolin and L-carnitine
• ✓ Includes green tea and African mango extracts

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One of the ingredients that caught our attention was forskolin, a compound found in coleus root. In one small study, men taking a forskolin-containing extract lost more body fat than those taking a placebo, even though the groups’ scale weights showed no significant difference. Other small studies have found mixed results. What interested us was the process behind that finding, right down to the signal that helps a fat cell release what it’s stored. That’s where we’ll start. Human study · NIH research review

1. Forskolin and How Your Body Releases Stored Fat

Picture yourself out for a brisk walk. Your muscles need fuel, and fat can supply some of it. To tap into stored fat, your body first breaks it down into smaller pieces called fatty acids. Those fatty acids can then travel through your bloodstream to your muscles.

We chose coleus root extract for Radical Metabolizer because it contains forskolin. Researchers study forskolin because it can raise levels of a chemical messenger called cAMP. Inside a fat cell, cAMP helps switch on enzymes that break down stored fat and release fatty acids. Your body can then use those fatty acids for fuel or store them again.

Once your body releases fatty acids, how do your cells put them to work? That’s the next step we considered when we chose L-carnitine for Radical Metabolizer.

2. L-Carnitine Helps Your Cells Use Fat for Fuel

Once your body releases stored fat, many of those fatty acids still need a way into the parts of your cells that turn them into energy. L-carnitine helps carry them there. We chose it because it plays a role in the next step after fat leaves storage. NIH carnitine fact sheet

3. Green Tea Leaf Extract Brings EGCG to the Formula

L-carnitine helps carry fatty acids into the parts of your cells that can use them for energy. When we looked at green tea leaf extract, we were interested in a related question. Could it affect how much fat your body uses during exercise?

In one small study, 12 men completed a 30-minute bike ride after taking green tea extract and again after taking a placebo. They used fat for fuel at a higher rate during the ride after taking the extract. That’s what caught our attention when we chose green tea leaf extract, a source of EGCG, for Radical Metabolizer. Green tea leaf extract contains epigallocatechin gallate (EGCG), one of green tea’s naturally occurring catechins. The study measured fuel use during a single workout. Cycling study · NIH review of green tea research

4. African Mango Seed Extract Brings Us Back to the Tape Measure

African mango seed extract was actually the starting point for Radical Metabolizer. What caught our eye was that early studies measured waist size as well as weight. Some reported reductions in both. Most of the trials had design limitations, but we were interested in what researchers could learn by looking beyond the number on the scale. African mango research review. We found that studies show it helps shrink stubborn belly fat, with participants losing inches off their waist and hips in just weeks!

5. Raspberry Ketones Caught Our Eye for a Different Reason

What does the scent of a raspberry have to do with fat metabolism? One of the compounds behind that familiar scent, raspberry ketone, caught our attention because of what happened when researchers added it to fat cells grown in the lab. The cells released more adiponectin, a hormone that helps regulate how the body uses fat and handles blood sugar. The researchers also saw the cells break down more stored fat and use more fatty acids for energy. Laboratory study

That’s why we included raspberry ketones in Radical Metabolizer. The study looked at two steps we were interested in when we built the formula: how fat comes out of storage and how cells use it for fuel. Those findings came from lab-grown cells. NIH review of raspberry ketone research

The Bottom Line

The next time you step on the scale, remember how much happens before that number appears. Your body is constantly storing, releasing, and using fuel. That process is what drew us to forskolin and helped us decide what the other four ingredients could bring to the formula.

We created Radical Metabolizer to fit alongside the habits that shape weight management over time, including how you eat and how often you move. Want to see how those five ingredients come together in each serving? 

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.