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146 reviews |
Original price $43.35 - Original price $43.35
Original price
$43.35 - $43.35
Current price $43.35
  • All-natural progesterone body creme derived from wild yam
  • Contains lavender essential oil

Note: Prescription required for shipment to Canada. 

Buy 3 or more to save 10%

Mix and match any three UNI KEY or Fat Flush brand products to save 10% instantly!


Balance Your Hormones Naturally*

ProgestaKey is an all-natural Progesterone Crème sourced from wild yam for menopausal and peri-menopausal support.* Each pump of this topical hormone balance creme conveniently delivers the recommended dosage of 20 mg of USP progesterone per pump and is scented with lavender essential oil.

Progesterone, not estrogen, is often the first hormone to decline during the peri-menopausal years. According to Harvard research, it's estimated that by age 35, the typical woman is already deficient in progesterone.

Progesterone has benefits far beyond its role in menstrual cycles and pregnancy, and lack of this essential hormone can affect many of the body's systems.

Signs of progesterone deficiency:

  • Frequent hot flashes and night sweats*
  • Emotional Swings*
  • Weight gain, especially around the tummy*
  • Lack or decrease in sex drive*
  • Exhaustion/low energy*

Benefits of proper progesterone levels:

  • Reduction of menopausal symptoms
  • Improved hormone balance
  • Stimulation of bone formation and prevention of osteoporosis
  • Stabilization of zinc-copper balance
  • Enhanced sex drive
  • Metabolism of fat
  • Promotion of a sense of well-being

If you're unsure if you're in need of Progesterone, consider an at-home Salivary Hormone Test to evaluate your hormone levels.

ProgestaKey Ingredients:

Purified water, aloe vera gel, caprylic/capric triglycerides, natural progesterone USP, evening primrose oil, vitamin E acetate, MSM (methyl sulfonylmethane), isostearic acid, yarrow extract, cranberry extract, glyceryl stearate, shea butter, lecithin, glycerine USP, lavender essential oil, vanilla extract, allantoin, sorbic acid, and grapeseed extract.

IMPORTANT for Canadian Customers:  Due to Health Canada restrictions, Natural Progesterone Crème requires a prescription for shipment to Canada. In order for your order to be processed, send us a copy of a current prescription from a licensed physician in Canada. 


Q: Can I use this with other HRT?
A: Yes, though it may be a good idea to evaluate your hormone levels with a Salivary Hormone Test. Also, if using hormonal contraceptives, please use back up method of birth control.

Q: Do I have to use this forever?
A: Progesterone is important for many aspects of health in women of all ages- from balanced monthly cycles and mood swings to relieving hot flashes and night sweats and supporting healthy bones.* You may use ProgestaKey long term, or just as long as you want to help manage symptoms.

Q: Do I need to rotate the site of application?
A: Yes, we recommend rotating the site of application every week to prevent saturating the progesterone receptors in your skin. For instance, week one apply to chest and neck, week two to abdomen, week three to inner arms and inner thighs.

Q: My cycle is irregular. How do I decide when to start and stop ProgestaKey?
A: It's common for a woman's cycle to be as short as 20 days and as long as 40. Day 1 of your cycle is considered the first day of menstruation. The basic instructions for menstruating women advise using the creme from day 12 to 26. If your menses begins before day 26, simply stop using the creme when it begins, and resume again on day 12. If your menses is still happening by day 12, still begin using the creme as scheduled. If you experience spotting, stick to the regular schedule. If the spotting is so prevalent that you can't discern your true menses, simply use the creme for two weeks each month and keep consistent to that schedule.

Q: I've had a hysterectomy. How should I use ProgestaKey?
A: Please follow the directions for menopausal women, applying the creme for 25 consecutive days and then taking a 5 day break.

Q: I want to do the salivary hormone test. Can I still use ProgestaKey?
A: To achieve an accurate reading, we recommend abstaining from the creme for at least 3-5 days prior to collecting your saliva sample. Menstruating women should collect their saliva on days 19, 20, or 21 of their cycle, so consider skipping ProgestaKey all together that cycle. Menopausal women can collect their saliva any day of the month, so aim to do so on the final day of the 5 day break from ProgestaKey.



For optimum absorption, apply ProgestaKey to the neck area. Refer to the 'Suggested Use' section on the label for more complete directions regarding specific frequency and dosage according to your age and stage of life. Wash hands after applying.


Purified water, aloe vera gel, caprylic/capric triglycerides, natural progesterone USP, evening primrose oil, vitamin E acetate, MSM (methyl sulfonylmethane), isostearic acid, yarrow extract, cranberry extract, glyceryl stearate, shea butter, lecithin, glycerine USP, lavender essential oil, vanilla extract, allantoin, sorbic acid, and grapeseed extract.



May not be appropriate for pregnant and/or nursing women. If using ProgestaKey with birth control, it is recommended for use only once every 3 days during the last 2 weeks of your cycle. Consult your health care practitioner for specific instructions.

Why Buy From Us?

ProgestaKey is manufactured in the USA at a Good Manufacturing Practices (GMP) and FDA registered facility. Each finished product must meet stringent quality standards.

Every batch of ProgestaKey is then third-party tested to confirm it meets the highest standards for purity, and every third batch is third-party tested for heavy metals.

100% Satisfaction Guarantee

We believe you’ll love the benefits of ProgestaKey. Try ProgestaKey today with complete confidence thanks to our 100% Satisfaction 90-Day Money-Back Guarantee.

If you’re dissatisfied with ProgestaKey for any reason please give us a call at 800-888-4353 or email and we’ll make it right.

Customer Reviews
4.7 Based on 146 Reviews
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Filter Reviews:
Brenna V.
United States United States

Amazing! Foremost, it WORKS!

I’ve had some hot flashes and was easily irritable towards people, even with myself. After using for 2 days, I was no longer having hot flashes and being irritable. Also, it helped with my migraines that was related to perimenopausal phase. You definitely won’t regret it!


UNI KEY Health

This is great, Brenna! We're so happy to hear that you're feeling better with Progesta-Key! Thank you for the great review :) ~UNI KEY Staff

Kathleen M.
United States United States


Yes I have been using this product for about 16 years and do believe that it works. I would recommend this product to anyone who is having hot flashes and night sweats. Kathy


UNI KEY Health

Thank you for the great review, Kathy! We're so happy to hear that Progesta-Key has been working for you all of these years! Thanks for making us a part of your health journey! In good health, UNI KEY Staff

Jennifer D.
United States United States

Progesta Key

I love using Protestant Key! I appreciate the natural form of progesterone and feel my hormones are more balanced because of using it. I am recovering from a bad concussion, and it is important that all areas of my life are in balance. Progesta Key is a special Key to my health and recovery

Kimberly H.
United States United States

Best on the market

I have been using your Progestakey for over 12 years. Twice I decided to try a different brand, and both times went back to your product. There was no comparison to how well Progestakey works for me! Thanks!

Brenda H.
United States United States

Progesta is Key

I have been using natural progesterone cream for 20 plus years to help balance hormones. IT has helped me through conceiving my son, carrying him full term, and going through menopause. When my first distributor no longer carried the brand I was using, I turned to Unikey's ProgestaKey. It is important to me to know it is made with the finest quality of products in the right amount of dosage as I am continuing to age. My 92 year old mother still uses it for her osteoporosis too.

Anna S.
United States United States

Progesterone Cream

Great product! Easy to apply and doesn't contain harsh chemicals!